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Lysosomes (Medical Intelligence Unit)
Lysosomes (Medical Intelligence Unit)
Date: 12 Mar 2007, 12:40
Lysosomes are membrane-surrounded organelles which are present in all animal cells. The importance of

this organelle is underlined by an increasing number of human diseases, which are associated with an

impaired function of the lysosomal compartment.

This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the

biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane

in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal

storage disorders, and new concepts on how to treat these diseases. In addition to these these classical

topics, new insights into lysosomal functions are covered by chapters dealing with specialized lysosomes

involved in bone resorption and plasma membrane repair, the lysosomal transciptome, and proteome and the

emerging role of lysosomes in special forms of autophagy.

This book will provide readers with a comprehensive overview into how this fascinating organelle works

and how research in the field is developing.


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