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DNA Methylation: Approaches and Applications
DNA Methylation: Approaches and Applications
Date: 17 Dec 2006, 21:19
Pages: 240

DNA Methylation: Approaches, Methods and Applications describes the relation DNA

methylation has to gene silencing in disease, and explores its promising role in treating

cancer. Written by leaders in the field, this exceptional compilation of articles outlines

the best techniques to use when addressing questions concerning the cytosine methylation

status of genomic DNA. It includes concepts, experimental models, and clinical uses of

demethylating agents. The book provides a balance between articles clarifying

methodological details and more general review chapters that offer broad biological

perspectives on DNA methylation. This is an invaluable handbook for researchers and

clinicians interested in genetics and molecular biology, particularly epigenetic therapies

and gene silencing.


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