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Capillary Electrophoresis of Nucleic Acids, Vol. II
Capillary Electrophoresis of Nucleic Acids, Vol. II
Date: 29 Dec 2006, 20:35
Practical Applications of Capillary Electrophoresis
(Methods in Molecular Biology)
Pages: 408, 2.4 MB

An outstanding panel of hands-on experts and developers of CE equipment describe in

step-by-step fashion their best cutting-edge methods for the detection and analysis of DNA

mutations and modifications, ranging from precise DNA loci to entire genomes of organisms.

This second volume of the set, Practical Applications of Capillary Electrophoresis, covers

techniques for high-throughput analysis of DNA fragments using SNP detection, mutation

detection, DNA sequencing methods, and DNA-ligand interactions. Several chapters also

discuss CE analysis at elevated temperatures and the use of micro-CE and array-CE devices.

The companion volume, Introduction to the Capillar Electrophoresis of Nucliec Acids,

offers readily reproducible methods for the analysis of small oligonucleotides and

modified nucleotides, and time-tested advice on instrumentation, signal detection, the

capillary environment, and the integration of mass spectrometry with CE. Comprehensive and

up-to-date, the paired volumes of Capillary Electrophoresis of Nucleic Acids offer an

authoritative guide with easy access to fast, versatile, reliable, and powerful

technologies for all those basic and clinical investigators analyzing DNA variation today.


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